@article {2009|2010, title = {{N}icotinic receptors: allosteric transitions and therapeutic targets in the nervous system}, journal = {Nat. Rev. Drug Discov.}, volume = {8}, number = {9}, year = {2009}, month = {sep}, pages = {733{\textendash}750}, publisher = {Nature Publishing Group}, author = {Antoine Taly and Corringer, P. J. and Guedin, D. and Lestage, P. and Jean-Pierre Changeux} } @article {2008|1999, title = {{F}unctional organization and conformational dynamics of the nicotinic receptor: a plausible structural interpretation of myasthenic mutations}, journal = {Ann. N. Y. Acad. Sci.}, volume = {1132}, number = {1}, year = {2008}, pages = {42{\textendash}52}, publisher = {Wiley Online Library}, author = {Antoine Taly and Jean-Pierre Changeux} } @article {2008|2012, title = {Nicotinic receptors, allosteric proteins and medicine}, journal = {Trends Mol. Med.}, volume = {14}, number = {3}, year = {2008}, month = {mar}, pages = {93{\textendash}102}, publisher = {Elsevier}, author = {Jean-Pierre Changeux and Antoine Taly} } @article {2007|2001, title = {{D}ocking of alpha-cobratoxin suggests a basal conformation of the nicotinic receptor}, journal = {Biochem. Biophys. Res. Commun.}, volume = {359}, number = {3}, year = {2007}, month = {aug}, pages = {413{\textendash}418}, publisher = {Academic Press}, author = {Konstantakaki, M. and Jean-Pierre Changeux and Antoine Taly} } @article {2007|1728, title = {{A} prokaryotic proton-gated ion channel from the nicotinic acetylcholine receptor family}, journal = {Nature}, volume = {445}, number = {7123}, year = {2007}, month = {jan}, pages = {116{\textendash}119}, author = {Bocquet, N. and Prado de Carvalho, L. and Cartaud, J. and Neyton, J. and Le Poupon, C. and Antoine Taly and Grutter, T. and Jean-Pierre Changeux and Corringer, P. J.} } @article {2006|2008, title = {{I}dentification of two critical residues within the {C}ys-loop sequence that determine fast-gating kinetics in a pentameric ligand-gated ion channel}, journal = {J. Mol. Neurosci.}, volume = {30}, number = {1-2}, year = {2006}, pages = {63{\textendash}64}, publisher = {Springer}, author = {Grutter, T. and de Carvalho, L. P. and Dufresne, V. and Antoine Taly and Jean-Pierre Changeux} } @article {2006|1754, title = {{I}mplications of the quaternary twist allosteric model for the physiology and pathology of nicotinic acetylcholine receptors}, journal = {Proc. Natl. Acad. Sci. U.s.a.}, volume = {103}, number = {45}, year = {2006}, month = {nov}, pages = {16965{\textendash}16970}, author = {Antoine Taly and Corringer, P. J. and Grutter, T. and Prado de Carvalho, L. and Karplus, M. and Jean-Pierre Changeux} } @article {2006|1757, title = {Implications of the quaternary twist allosteric model for the physiology and pathology of nicotinic acetylcholine receptors}, journal = {Proceedings of the National Academy of Sciences}, volume = {103}, number = {45}, year = {2006}, pages = {16965{\textendash}16970}, publisher = {National Acad Sciences}, author = {Antoine Taly and Corringer, Pierre-Jean and Grutter, Thomas and De Carvalho, Lia Prado and Karplus, Martin and Jean-Pierre Changeux} } @article {2005|1631, title = {{A} chimera encoding the fusion of an acetylcholine-binding protein to an ion channel is stabilized in a state close to the desensitized form of ligand-gated ion channels}, journal = {C. R. Biol.}, volume = {328}, number = {3}, year = {2005}, month = {mar}, pages = {223{\textendash}234}, author = {Grutter, T. and Prado de Carvalho, L. and Virginie, D. and Antoine Taly and Fischer, M. and Jean-Pierre Changeux} } @article {2005|2011, title = {{M}olecular tuning of fast gating in pentameric ligand-gated ion channels}, journal = {Proc. Natl. Acad. Sci. U.s.a.}, volume = {102}, number = {50}, year = {2005}, month = {dec}, pages = {18207{\textendash}18212}, publisher = {National Acad Sciences}, author = {Grutter, T. and de Carvalho, L. P. and Dufresne, V. and Antoine Taly and Edelstein, S. J. and Jean-Pierre Changeux} } @article {2005|2003, title = {{N}ormal mode analysis suggests a quaternary twist model for the nicotinic receptor gating mechanism}, journal = {Biophys. J.}, volume = {88}, number = {6}, year = {2005}, month = {jun}, pages = {3954{\textendash}3965}, publisher = {Cell Press}, author = {Antoine Taly and Delarue, M. and Grutter, T. and Nilges, M. and Le Novere, N. and Corringer, P. J. and Jean-Pierre Changeux} } @article {2004|1647, title = {Critical role of the C-terminal segment in the maturation and export to the cell surface of the homopentameric $\alpha$7{\textendash}5HT3A receptor}, journal = {Eur. J. Neurosci.}, volume = {20}, number = {8}, year = {2004}, pages = {2022{\textendash}2030}, publisher = {Wiley Online Library}, author = {Pons, S and Sallette, J and Bourgeois, JP and Antoine Taly and Jean-Pierre Changeux and Devillers-Thi{\'e}ry, A} }