@article {2019|2076,
	title = {Glutathionylation primes soluble glyceraldehyde-3-phosphate dehydrogenase for late collapse into insoluble aggregates.},
	journal = {Proc Natl Acad Sci U S A},
	volume = {116},
	year = {2019},
	month = {2019 12 17},
	pages = {26057-26065},
	abstract = {<p>Protein aggregation is a complex physiological process, primarily determined by stress-related factors revealing the hidden aggregation propensity of proteins that otherwise are fully soluble. Here we report a mechanism by which glycolytic glyceraldehyde-3-phosphate dehydrogenase of (AtGAPC1) is primed to form insoluble aggregates by the glutathionylation of its catalytic cysteine (Cys149). Following a lag phase, glutathionylated AtGAPC1 initiates a self-aggregation process resulting in the formation of branched chains of globular particles made of partially misfolded and totally inactive proteins. GSH molecules within AtGAPC1 active sites are suggested to provide the initial destabilizing signal. The following removal of glutathione by the formation of an intramolecular disulfide bond between Cys149 and Cys153 reinforces the aggregation process. Physiological reductases, thioredoxins and glutaredoxins, could not dissolve AtGAPC1 aggregates but could efficiently contrast their growth. Besides acting as a protective mechanism against overoxidation, S-glutathionylation of AtGAPC1 triggers an unexpected aggregation pathway with completely different and still unexplored physiological implications.</p>
},
	issn = {1091-6490},
	doi = {10.1073/pnas.1914484116},
	author = {Zaffagnini, Mirko and Marchand, Christophe H and Malferrari, Marco and Murail, Samuel and Bonacchi, Sara and Genovese, Damiano and Montalti, Marco and Venturoli, Giovanni and Falini, Giuseppe and Marc Baaden and Lemaire, St{\'e}phane D and Fermani, Simona and Trost, Paolo}
}
@article {2013|1528,
	title = {{G}ame on, science - how video game technology may help biologists tackle visualization challenges},
	journal = {Plos One},
	volume = {8},
	number = {3},
	year = {2013},
	pages = {e57990},
	author = {Lv, Z. and Tek, A. and Da Silva, F. and Empereur-mot, C. and Matthieu Chavent and Marc Baaden}
}
@article {2011|1437,
	title = {GPU-accelerated atom and dynamic bond visualization using HyperBalls: a unified algorithm for balls, sticks and hyperboloids},
	journal = {J. Comput. Chem.},
	volume = {32},
	number = {13},
	year = {2011},
	month = {oct},
	pages = {2924{\textendash}2935},
	doi = {10.1002/jcc.21861/abstract},
	author = {Matthieu Chavent and A. Vanel and A. Tek and B. L{\'e}vy and S. Robert and B. Raffin and Marc Baaden}
}
@article {2011|1393,
	title = {GPU-powered tools boost molecular visualization},
	journal = {Briefings Bioinf.},
	volume = {12},
	year = {2011},
	month = {feb},
	pages = {689{\textendash}701},
	author = {Matthieu Chavent and B. L{\'e}vy and M. Krone and K. Bidmon and J. P. Nomin{\'e} and T. Ertl and Marc Baaden}
}
