@article {2017|2037,
	title = {Multifunctional energy landscape for a DNA G-quadruplex: An evolved molecular switch.},
	journal = {J Chem Phys},
	volume = {147},
	year = {2017},
	month = {2017 Oct 21},
	pages = {152715},
	abstract = {<p>We explore the energy landscape for a four-fold telomere repeat, obtaining interconversion pathways between six experimentally characterised G-quadruplex topologies. The results reveal a multi-funnel system, with a variety of intermediate configurations and misfolded states. This organisation is identified with the intrinsically multi-functional nature of the system, suggesting a new paradigm for the classification of such biomolecules and clarifying issues regarding apparently conflicting experimental results.</p>
},
	issn = {1089-7690},
	doi = {10.1063/1.4997377},
	author = {Cragnolini, Tristan and Chakraborty, Debayan and Sponer, Jiri and Philippe Derreumaux and Pasquali, Samuela and Wales, David J}
}
